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Novel role for a bacterial nucleoid protein in translation of mRNAs with suboptimal ribosome-binding sites

In Escherichia coli, the major nucleoid protein H-NS limits transcription by acting as a repressor or transcriptional silencer, presumably by its ability to close the looped chromosome domains in the nucleoid through DNA–protein–DNA bridging. Here, we demonstrate the direct involvement of H-NS as a...

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Detalhes bibliográficos
Main Authors: Park, Hyun-Sook, Östberg, Yngve, Johansson, Jörgen, Wagner, E. Gerhart H., Uhlin, Bernt Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895194/
https://ncbi.nlm.nih.gov/pubmed/20595230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.576310
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