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Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome
Fragile X syndrome (FXS), a common inherited form of mental impairment and autism, is caused by transcriptional silencing of the fragile X mental retardation 1 (FMR1) gene. Earlier studies have identified a role for aberrant synaptic plasticity mediated by the metabotropic glutamate receptors (mGluR...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895119/ https://ncbi.nlm.nih.gov/pubmed/20534533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002262107 |
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