The t(14;20) is a poor prognostic factor in myeloma but is associated with long-term stable disease in monoclonal gammopathies of undetermined significance

A large series of plasma cell dyscrasias (n=2207) was examined for translocations which deregulate the MAF genes, t(14;20)(q32;q12) and t(14;16)(q32;q23), and their disease behavior was compared to a group characterized by the t(4;14)(p16;q32) where CCND2 is also up-regulated. The t(14;20) showed lo...

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Autors principals: Ross, Fiona M., Chiecchio, Laura, Dagrada, GianPaolo, Protheroe, Rebecca K.M., Stockley, David M., Harrison, Christine J., Cross, Nicholas C.P., Szubert, Alex J., Drayson, Mark T., Morgan, Gareth J.
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2010
Matèries:
Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895050/
https://ncbi.nlm.nih.gov/pubmed/20410185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.016329
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