Loss of 1p and rearrangement of MYC are associated with progression of smouldering myeloma to myeloma: sequential analysis of a single case

We report serial genetic studies on a young female patient initially diagnosed with asymptomatic smouldering myeloma who progressed to symptomatic myeloma 4.5 years after presentation. An unbalanced translocation, der(14)t(4;14)(p16;q32), was initially found in all plasma cells plus deletions of oth...

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Bibliographische Detailangaben
Hauptverfasser: Chiecchio, Laura, Dagrada, Gian Paolo, Protheroe, Rebecca K.M., Stockley, David M., Smith, Alastair G., Orchard, Kim H., Cross, Nicholas C.P., Harrison, Christine J., Ross, Fiona M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2009
Schlagworte:
Brief Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704316/
https://ncbi.nlm.nih.gov/pubmed/19454499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2008.004440
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