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Inhibition of StearoylCoA Desaturase Activity Blocks Cell Cycle Progression and Induces Programmed Cell Death in Lung Cancer Cells

Lung cancer is the most frequent form of cancer. The survival rate for patients with metastatic lung cancer is ∼5%, hence alternative therapeutic strategies to treat this disease are critically needed. Recent studies suggest that lipid biosynthetic pathways, particularly fatty acid synthesis and des...

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Detalhes bibliográficos
Main Authors: Hess, Daniel, Chisholm, Jeffrey W., Igal, R. Ariel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894866/
https://ncbi.nlm.nih.gov/pubmed/20613975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011394
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