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Inhibition of StearoylCoA Desaturase Activity Blocks Cell Cycle Progression and Induces Programmed Cell Death in Lung Cancer Cells

Lung cancer is the most frequent form of cancer. The survival rate for patients with metastatic lung cancer is ∼5%, hence alternative therapeutic strategies to treat this disease are critically needed. Recent studies suggest that lipid biosynthetic pathways, particularly fatty acid synthesis and des...

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Bibliografiske detaljer
Main Authors: Hess, Daniel, Chisholm, Jeffrey W., Igal, R. Ariel
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894866/
https://ncbi.nlm.nih.gov/pubmed/20613975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011394
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