No association between variation in the NR4A1 gene locus and metabolic traits in white subjects at increased risk for type 2 diabetes

BACKGROUND: The nuclear receptor NR4A1 is implicated in metabolic regulation in insulin-sensitive tissues, such as liver, adipose tissue, and skeletal muscle. Functional loss of NR4A1 results in insulin resistance and enhanced intramuscular and hepatic lipid content. Therefore, we investigated in a...

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Main Authors: Müssig, Karsten, Machicao, Fausto, Machann, Jürgen, Schick, Fritz, Claussen, Claus D, Stefan, Norbert, Fritsche, Andreas, Häring, Hans-Ulrich, Staiger, Harald
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894787/
https://ncbi.nlm.nih.gov/pubmed/20525362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-84
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