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Gene trap mutation of murine Outer dense fiber protein-2 gene can result in sperm tail abnormalities in mice with high percentage chimaerism

BACKGROUND: Outer dense fiber protein 2, Odf2, is a major component of the outer dense fibers, ODF, in the flagellum of spermatozoa. ODF are associated with microtubule doublets that form the axoneme. We recently demonstrated that tyrosine phosphorylation of Odf2 is important for sperm motility. In...

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Bibliographische Detailangaben
Hauptverfasser: Tarnasky, Heide, Cheng, Min, Ou, Young, Thundathil, Jacob C, Oko, Richard, van der Hoorn, Frans A
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894780/
https://ncbi.nlm.nih.gov/pubmed/20550699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-10-67
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