Gene trap mutation of murine Outer dense fiber protein-2 gene can result in sperm tail abnormalities in mice with high percentage chimaerism

BACKGROUND: Outer dense fiber protein 2, Odf2, is a major component of the outer dense fibers, ODF, in the flagellum of spermatozoa. ODF are associated with microtubule doublets that form the axoneme. We recently demonstrated that tyrosine phosphorylation of Odf2 is important for sperm motility. In...

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Autores principales: Tarnasky, Heide, Cheng, Min, Ou, Young, Thundathil, Jacob C, Oko, Richard, van der Hoorn, Frans A
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
Materias:
Research article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894780/
https://ncbi.nlm.nih.gov/pubmed/20550699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-10-67
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