Corticosteroid suppression of lipoxin A(4 )and leukotriene B(4)from alveolar macrophages in severe asthma

BACKGROUND: An imbalance in the generation of pro-inflammatory leukotrienes, and counter-regulatory lipoxins is present in severe asthma. We measured leukotriene B(4 )(LTB(4)), and lipoxin A(4 )(LXA(4)) production by alveolar macrophages (AMs) and studied the impact of corticosteroids. METHODS: AMs...

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Huvudupphovsmän: Bhavsar, Pankaj K, Levy, Bruce D, Hew, Mark J, Pfeffer, Michael A, Kazani, Shamsah, Israel, Elliot, Chung, Kian Fan
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2010
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894769/
https://ncbi.nlm.nih.gov/pubmed/20529300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-71
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