Pharmacological studies of the mechanism and function of interleukin-1β-induced miRNA-146a expression in primary human airway smooth muscle

BACKGROUND: Despite the widespread induction of miR-146a during the innate immune response little is known regarding its biogenesis, function and mechanism. We have therefore examined the role of miR-146a during the interleukin (IL)-1β-stimulated IL-6 and IL-8 release and proliferation in primary hu...

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Bibliografiske detaljer
Main Authors: Larner-Svensson, Hanna M, Williams, Andrew E, Tsitsiou, Eleni, Perry, Mark M, Jiang, Xiaoying, Chung, Kian F, Lindsay, Mark A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894768/
https://ncbi.nlm.nih.gov/pubmed/20525168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-11-68
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