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Hematopoietic Origin of Pathological Grooming in Hoxb8 Mutant Mice
Mouse Hoxb8 mutants show unexpected behavior manifested by compulsive grooming and hair removal similar to humans with OCD-spectrum disorder trichotillomania. Since Hox gene disruption often has pleiotropic effects, the root cause of this behavioral deficit was unclear. Here we report that, in the b...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2894573/ https://ncbi.nlm.nih.gov/pubmed/20510925 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.03.055 |
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