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Hematopoietic Origin of Pathological Grooming in Hoxb8 Mutant Mice

Mouse Hoxb8 mutants show unexpected behavior manifested by compulsive grooming and hair removal similar to humans with OCD-spectrum disorder trichotillomania. Since Hox gene disruption often has pleiotropic effects, the root cause of this behavioral deficit was unclear. Here we report that, in the b...

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Detaylı Bibliyografya
Asıl Yazarlar: Chen, Shau-Kwaun, Tvrdik, Petr, Peden, Erik, Cho, Scott, Wu, Sen, Spangrude, Gerald, Capecchi, Mario R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894573/
https://ncbi.nlm.nih.gov/pubmed/20510925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.03.055
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