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RNAi Knockdown of Interleukin-6 Attenuates Cold-Induced Hypertension

The purpose of this study was to determine the role of the pro-inflammatory cytokine IL-6 in cold-induced hypertension (CIH). Four groups of male Sprague Dawley rats were used (6 rats/group). After blood pressure (BP) was stabilized, 3 groups received intravenous delivery of AAV carrying IL-6shRNA,...

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Bibliographic Details
Main Authors: Crosswhite, Patrick, Sun, Zhongjie
Format: Artigo
Language:Inglês
Published: 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894564/
https://ncbi.nlm.nih.gov/pubmed/20385973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.109.146902
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