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An Efficient Total Synthesis of Ammosamide B
[Image: see text] A total synthesis of ammosamide B, a metabolite of the marine-derived Streptomyces strain CNR-698, has been executed in nine steps and 6.9% overall yield. The key step involves the condensation of a 4,6-diBoc protected 1,3,4,6-tetraaminobenzene derivative with dimethyl 2-ketoglutac...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2894265/ https://ncbi.nlm.nih.gov/pubmed/20515072 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol101215x |
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