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An Efficient Total Synthesis of Ammosamide B

[Image: see text] A total synthesis of ammosamide B, a metabolite of the marine-derived Streptomyces strain CNR-698, has been executed in nine steps and 6.9% overall yield. The key step involves the condensation of a 4,6-diBoc protected 1,3,4,6-tetraaminobenzene derivative with dimethyl 2-ketoglutac...

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Autori principali: Reddy, P. V. Narasimha, Banerjee, Biplab, Cushman, Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894265/
https://ncbi.nlm.nih.gov/pubmed/20515072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol101215x
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