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Conserved residue clusters at protein-protein interfaces and their use in binding site identification

BACKGROUND: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of structural co-operativity between spatially neighboring residues and it has previously been shown that conserved residues o...

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Bibliografiske detaljer
Main Authors: Guharoy, Mainak, Chakrabarti, Pinak
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894039/
https://ncbi.nlm.nih.gov/pubmed/20507585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-286
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