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P38 Mitogen-activated Protein Kinase Activity Is Required during Mitosis for Timely Satisfaction of the Mitotic Checkpoint But Not for the Fidelity of Chromosome Segregation

Although p38 activity is reported to be required as cells enter mitosis for proper spindle assembly and checkpoint function, its role during the division process remains controversial in lieu of direct data. We therefore conducted live cell studies to determine the effect on mitosis of inhibiting or...

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Detalhes bibliográficos
Main Authors: Lee, Kyunghee, Kenny, Alison E., Rieder, Conly L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893980/
https://ncbi.nlm.nih.gov/pubmed/20462950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-02-0125
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