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MMP13 as a stromal mediator in controlling persistent angiogenesis in skin carcinoma

Matrix metalloproteinases (MMPs) such as MMP13 promote tumour growth and progression by mediating extracellular matrix (ECM) reorganization and regulating the biological activity of cytokines. Using Mmp13−/− mice, we demonstrate an essential role of this single collagenase for highly malignant and i...

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Detalhes bibliográficos
Main Authors: Lederle, Wiltrud, Hartenstein, Bettina, Meides, Alice, Kunzelmann, Heike, Werb, Zena, Angel, Peter, Mueller, Margareta M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893794/
https://ncbi.nlm.nih.gov/pubmed/19892798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp248
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