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MMP13 as a stromal mediator in controlling persistent angiogenesis in skin carcinoma
Matrix metalloproteinases (MMPs) such as MMP13 promote tumour growth and progression by mediating extracellular matrix (ECM) reorganization and regulating the biological activity of cytokines. Using Mmp13−/− mice, we demonstrate an essential role of this single collagenase for highly malignant and i...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2893794/ https://ncbi.nlm.nih.gov/pubmed/19892798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp248 |
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