MMP-13 Plays a Role in Keratinocyte Migration, Angiogenesis, and Contraction in Mouse Skin Wound Healing

Matrix metalloproteinases (MMPs) have been implicated in wound healing. To analyze the roles of MMP-9 and MMP-13 in wound healing, we generated full-thickness cutaneous wounds in MMP-9 knockout (KO), MMP-13 KO, MMP-9/13 double KO, and wild-type mice. Macroscopic wound closure was delayed in all of t...

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Detalhes bibliográficos
Main Authors: Hattori, Noriko, Mochizuki, Satsuki, Kishi, Kazuo, Nakajima, Tatsuo, Takaishi, Hironari, D'Armiento, Jeanine, Okada, Yasunori
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716954/
https://ncbi.nlm.nih.gov/pubmed/19590036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.081080
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