An Akt- and Fra-1-Dependent Pathway Mediates Platelet-Derived Growth Factor-Induced Expression of Thrombomodulin, a Novel Regulator of Smooth Muscle Cell Migration

Overdistension of hollow organs evokes pathological changes characterized by smooth muscle remodeling. Mechanical stimuli induce smooth muscle cell (SMC) growth through acute activation of signaling cascades and by increased expression of soluble mitogens. Physical forces have also been implicated i...

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Detalhes bibliográficos
Main Authors: Ramachandran, Aruna, Ranpura, Sandeep A., Gong, Edward M., Mulone, Michelle, Cannon, Glenn M., Adam, Rosalyn M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893656/
https://ncbi.nlm.nih.gov/pubmed/20472895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090772
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