An Akt- and Fra-1-Dependent Pathway Mediates Platelet-Derived Growth Factor-Induced Expression of Thrombomodulin, a Novel Regulator of Smooth Muscle Cell Migration

Overdistension of hollow organs evokes pathological changes characterized by smooth muscle remodeling. Mechanical stimuli induce smooth muscle cell (SMC) growth through acute activation of signaling cascades and by increased expression of soluble mitogens. Physical forces have also been implicated i...

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Autors principals: Ramachandran, Aruna, Ranpura, Sandeep A., Gong, Edward M., Mulone, Michelle, Cannon, Glenn M., Adam, Rosalyn M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2010
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893656/
https://ncbi.nlm.nih.gov/pubmed/20472895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090772
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