Early Growth Response-1 Induces and Enhances Vascular Endothelial Growth Factor-A Expression in Lung Cancer Cells

Vascular endothelial growth factor-A (VEGF-A) is crucial for angiogenesis, vascular permeability, and metastasis during tumor development. We demonstrate here that early growth response-1 (EGR-1), which is induced by the extracellular signal–regulated kinase (ERK) pathway activation, activates VEGF-...

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Detalhes bibliográficos
Main Authors: Shimoyamada, Hiroaki, Yazawa, Takuya, Sato, Hanako, Okudela, Koji, Ishii, Jun, Sakaeda, Masashi, Kashiwagi, Korehito, Suzuki, Takehisa, Mitsui, Hideaki, Woo, Tetsukan, Tajiri, Michihiko, Ohmori, Takahiro, Ogura, Takashi, Masuda, Munetaka, Oshiro, Hisashi, Kitamura, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893652/
https://ncbi.nlm.nih.gov/pubmed/20489156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091164
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