Down-Regulation of DUSP6 Expression in Lung Cancer —Its Mechanism and Potential Role in Carcinogenesis

Our preliminary studies revealed that oncogenic KRAS (KRAS/V12) dramatically suppressed the growth of immortalized airway epithelial cells (NHBE-T, with viral antigen-inactivated p53 and RB proteins). This process appeared to be a novel event, different from the so-called premature senescence that i...

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Detalhes bibliográficos
Main Authors: Okudela, Koji, Yazawa, Takuya, Woo, Tetsukan, Sakaeda, Masashi, Ishii, Jun, Mitsui, Hideaki, Shimoyamada, Hiroaki, Sato, Hanako, Tajiri, Michihiko, Ogawa, Nobuo, Masuda, Munetaka, Takahashi, Takashi, Sugimura, Haruhiko, Kitamura, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716981/
https://ncbi.nlm.nih.gov/pubmed/19608870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080489
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