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Identification of the homologous beige and Chediak–Higashi syndrome genes
Vesicular transport to and from the lysosome and late endosome is defective in patients with Chediak–Higashi syndrome (CHS) and in mutant beige (bg) mice1–4. CHS and bg cells have giant, perinuclear vesicles with characterises of late endosomes and lysosomes that arise from dysregulated homotypic fu...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1996
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2893578/ https://ncbi.nlm.nih.gov/pubmed/8717042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/382262a0 |
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