The Chediak-Higashi protein interacts with SNARE complex and signal transduction proteins.

BACKGROUND:Chediak-Higashi syndrome (CHS) is an inherited immunodeficiency disease characterized by giant lysosomes and impaired leukocyte degranulation. CHS results from mutations in the lysosomal trafficking regulator (LYST) gene, which encodes a 425-kD cytoplasmic protein of unknown function. The...

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Detalhes bibliográficos
Main Authors: Tchernev, Velizar T., Mansfield, Traci A., Giot, Loic, Kumar, A. Madan, Nandabalan, Krishnan, Li, Ying, Mishra, Vishnu S., Detter, John C., Rothberg, Jonathan M., Wallace, Margaret R., Southwick, Frederick S., Kingsmore, Stephen F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2039936/
https://ncbi.nlm.nih.gov/pubmed/11984006
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