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Manipulation of Electrostatic and Saccharide Linker Interactions in the Design of Efficient Glycopolypeptide-Based Cholera Toxin Inhibitors

[Image: see text] Multivalent, glycopolymer inhibitors designed for the treatment of disease and pathogen infection have shown improvements in binding correlated with general changes in glycopolymer architecture and composition. We have previously demonstrated that control of glycopolypeptide backbo...

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Hlavní autoři: Maheshwari, Ronak, Levenson, Eric A., Kiick, Kristi L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893567/
https://ncbi.nlm.nih.gov/pubmed/19780061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mabi.200900182
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