Complement activation mediates cetuximab inhibition of non-small cell lung cancer tumor growth in vivo

BACKGROUND: Cetuximab, an antibody targeting the epidermal growth factor receptor (EGFR), increases survival in patients with advanced EGFR-positive non-small cell lung cancer when administrated in combination with chemotherapy. In this study, we investigated the role of complement activation in the...

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Detaylı Bibliyografya
Asıl Yazarlar: Hsu, Yi-Fan, Ajona, Daniel, Corrales, Leticia, Lopez-Picazo, Jose M, Gurpide, Alfonso, Montuenga, Luis M, Pio, Ruben
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2010
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893457/
https://ncbi.nlm.nih.gov/pubmed/20529262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-139
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