Complementing the Cancer-Immunity Cycle

Reactivation of cytotoxic CD8+ T-cell responses has set a new direction for cancer immunotherapy. Neutralizing antibodies targeting immune checkpoint programmed cell death protein 1 (PD-1) or its ligand (PD-L1) have been particularly successful for tumor types with limited therapeutic options such a...

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Detalhes bibliográficos
Main Authors: Ruben Pio, Daniel Ajona, Sergio Ortiz-Espinosa, Alberto Mantovani, John D. Lambris
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-04-01
Colecção:Frontiers in Immunology
Assuntos:
cancer immunity
immunotherapy
complement system
C3a
C5a
C1q
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2019.00774/full
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