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Non-inferiority Trial Design and Analysis with an Ordered Three-Level Categorical Endpoint

This paper extends standard methodology for non-inferiority trial design from a binary endpoint to an ordered three-level endpoint: such as “success”, “intermediate”, and “failure”. A metric that summarizes outcome on this endpoint is proposed, and the corresponding sample size requirements are pres...

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Detalhes bibliográficos
Main Authors: Brittain, Erica, Hu, Zonghui
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893351/
https://ncbi.nlm.nih.gov/pubmed/20183434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543400902964142
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