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Detection of JC virus DNA and proteins in bone marrow of HIV-positive and HIV-negative patients: implications for viral latency and neurotropic transformation

BACKGROUND: We sought to determine the prevalence of JCV in bone marrow samples from HIV-positive and HIV-negative patients and whether the bone marrow is a site of latency and neurotropic transformation of JC virus, the agent of progressive multifocal leukoencephalopathy(PML). METHODS: We collected...

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Detalhes bibliográficos
Main Authors: Tan, Chen S, Dezube, Bruce J, Bhargava, Parul, Autissier, Patrick, Wuthrich, Christian, Miller, Janice, Koralnik, Igor J
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893283/
https://ncbi.nlm.nih.gov/pubmed/19434914
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