Poly-ICLC promotes the infiltration of effector T cells into intracranial gliomas via induction of CXCL10 in IFN-α and IFN-γ dependent manners

Stimulation of double-stranded (ds)RNA receptors can increase the effectiveness of cancer vaccines, but the underlying mechanisms are not completely elucidated. In this study, we sought to determine critical roles of host IFN-α and IFN-γ pathways in the enhanced therapeutic efficacy mediated by pept...

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Detalhes bibliográficos
Main Authors: Zhu, Xinmei, Fallert-Junecko, Beth A., Fujita, Mitsugu, Ueda, Ryo, Kohanbash, Gary, Kastenhuber, Edward R., McDonald, Heather A., Liu, Yan, Kalinski, Pawel, Reinhart, Todd A., Salazar, Andres M, Okada, Hideho
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893267/
https://ncbi.nlm.nih.gov/pubmed/20549206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-010-0876-3
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