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Identifying and Seeing beyond Multiple Sequence Alignment Errors Using Intra-Molecular Protein Covariation
BACKGROUND: There is currently no way to verify the quality of a multiple sequence alignment that is independent of the assumptions used to build it. Sequence alignments are typically evaluated by a number of established criteria: sequence conservation, the number of aligned residues, the frequency...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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Public Library of Science
2010
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2893159/ https://ncbi.nlm.nih.gov/pubmed/20596526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011082 |
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