MAPK-Activated Protein Kinase 2 Is Required for Mouse Meiotic Spindle Assembly and Kinetochore-Microtubule Attachment

MAPK-activated protein kinase 2 (MK2), a direct substrate of p38 MAPK, plays key roles in multiple physiological functions in mitosis. Here, we show for the first time the unique distribution pattern of MK2 in meiosis. Phospho-MK2 was localized on bipolar spindle minus ends and along the interstitia...

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Bibliographische Detailangaben
Hauptverfasser: Yuan, Ju, Xu, Bao-Zeng, Qi, Shu-Tao, Tong, Jing-Shan, Wei, Liang, Li, Mo, Ouyang, Ying-Chun, Hou, Yi, Schatten, Heide, Sun, Qing-Yuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893158/
https://ncbi.nlm.nih.gov/pubmed/20596525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011247
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