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T-lineage cells require the thymus, but not V(D)J recombination to produce IL-17A and regulate granulopoiesis in vivo
IL-17A and F regulate granulopoiesis and are produced by memory T cells. Recombinase activating gene (Rag)1(−/−) mice cannot produce mature T cells, but maintain normal neutrophil counts. Nude mice are neutropenic or have near-normal neutrophil counts, depending on the prevailing intestinal flora. A...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2893017/ https://ncbi.nlm.nih.gov/pubmed/19843951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900887 |
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