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Mycophenolate mofetil decreases atherosclerotic lesion size by depression of aortic T lymphocyte and IL-17-mediated macrophage accumulation
OBJECTIVE: This study tested whether immunosuppression with mycophenolate mofetil (MMF) inhibits atherosclerosis development in apolipoprotein-E–deficient (Apoe(−/−)) mice and investigated the mechanism. BACKGROUND: Chronic vascular inflammation involving both innate and adaptive immunity is central...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3378670/ https://ncbi.nlm.nih.gov/pubmed/21596236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2010.12.030 |
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