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Blockade of interleukin-23 signaling results in targeted protection of the colon and allows for separation of graft-versus-host and graft-versus-leukemia responses

Allogeneic stem cell transplantation is the most potent form of effective adoptive immunotherapy. The graft-versus-leukemia (GVL) effect mediated by the allogeneic graft, however, is typically coexpressed with graft-versus-host disease (GVHD), which is the major complication of allogeneic stem cell...

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Hlavní autoři: Das, Rupali, Komorowski, Richard, Hessner, Martin J., Subramanian, Hariharan, Huettner, Claudia S., Cua, Daniel, Drobyski, William R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892952/
https://ncbi.nlm.nih.gov/pubmed/20382845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-11-255422
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