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A Molecular Description of Flexibility in an Antibody Combining Site
Mature antibodies (Abs) that are exquisitely specific for virtually any foreign molecule may be produced by affinity maturation of naïve (or germline) Ab. However, the finite number of germline Ab available suggests that, in contrast to mature Ab, germline Ab must be broadly polyspecific so that the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2892760/ https://ncbi.nlm.nih.gov/pubmed/20455589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp906421v |
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