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A Molecular Description of Flexibility in an Antibody Combining Site
Mature antibodies (Abs) that are exquisitely specific for virtually any foreign molecule may be produced by affinity maturation of naïve (or germline) Ab. However, the finite number of germline Ab available suggests that, in contrast to mature Ab, germline Ab must be broadly polyspecific so that the...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2892760/ https://ncbi.nlm.nih.gov/pubmed/20455589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp906421v |
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