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A Molecular Description of Flexibility in an Antibody Combining Site

Mature antibodies (Abs) that are exquisitely specific for virtually any foreign molecule may be produced by affinity maturation of naïve (or germline) Ab. However, the finite number of germline Ab available suggests that, in contrast to mature Ab, germline Ab must be broadly polyspecific so that the...

詳細記述

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書誌詳細
主要な著者: Zimmermann, Jörg, Romesberg, Floyd E., Brooks, Charles L., Thorpe, Ian F.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892760/
https://ncbi.nlm.nih.gov/pubmed/20455589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp906421v
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