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Molecular evolution of affinity and flexibility in the immune system
The immune system responds to the introduction of foreign antigens by rapidly evolving antibodies with increasing affinity for the antigen (i.e., maturation). To investigate the factors that control this process at the molecular level, we have assessed the changes in flexibility that accompany ligan...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885586/ https://ncbi.nlm.nih.gov/pubmed/17488816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610064104 |
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