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Slug suppression induces apoptosis via Puma transactivation in rheumatoid arthritis fibroblast-like synoviocytes treated with hydrogen peroxide

Inadequate apoptosis contributes to synovial hyperplasia in rheumatoid arthritis (RA). Recent study shows that low expression of Puma might be partially responsible for the decreased apoptosis of fibroblast-like synoviocytes (FLS). Slug, a highly conserved zinc finger transcriptional repressor, is k...

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Bibliographic Details
Main Authors: Cha, Hoon-Suk, Bae, Eun-Kyung, Ahn, Joong Kyong, Lee, Jaejoon, Ahn, Kwang-Sung, Koh, Eun-Mi
Format: Artigo
Language:Inglês
Published: Korean Society for Biochemistry and Molecular Biology 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892596/
https://ncbi.nlm.nih.gov/pubmed/20418652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2010.42.6.044
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