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Variations of X Chromosome Inactivation Occur in Early Passages of Female Human Embryonic Stem Cells
X chromosome inactivation (XCI) is a dosage compensation mechanism essential for embryonic development and cell physiology. Human embryonic stem cells (hESCs) derived from inner cell mass (ICM) of blastocyst stage embryos have been used as a model system to understand XCI initiation and maintenance....
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2892515/ https://ncbi.nlm.nih.gov/pubmed/20593031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011330 |
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