Defective NKT Cell Activation by CD1d+ TRAMP Prostate Tumor Cells Is Corrected by Interleukin-12 with alpha-Galactosylceramide

Numerical and functional defects of invariant natural killer T cells (iNKT) have been documented in human and mouse cancers, resulting in a defect in IFN production in several malignancies. iNKT cells recognize glycolipids presented on CD1d molecules by dendritic and related cells, leading to their...

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Bibliographische Detailangaben
Hauptverfasser: Nowak, Michael, Arredouani, Mohammed S., Tun-Kyi, Adrian, Schmidt-Wolf, Ingo, Sanda, Martin G., Balk, Steven P., Exley, Mark A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892484/
https://ncbi.nlm.nih.gov/pubmed/20593019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011311
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