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Prion-like transmission of protein aggregates in neurodegenerative diseases

Neurodegenerative diseases are commonly associated with the accumulation of intracellular or extracellular protein aggregates. Recent studies suggest that these aggregates are capable of crossing cellular membranes and can directly contribute to the propagation of neurodegenerative disease pathogene...

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Autors principals: Brundin, Patrik, Melki, Ronald, Kopito, Ron
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892479/
https://ncbi.nlm.nih.gov/pubmed/20308987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm2873
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