Postnatal PPARδ Activation and Myostatin Inhibition Exert Distinct yet Complimentary Effects on the Metabolic Profile of Obese Insulin-Resistant Mice

BACKGROUND: Interventions for T2DM have in part aimed to mimic exercise. Here, we have compared the independent and combined effects of a PPARδ agonist and endurance training mimetic (GW501516) and a myostatin antibody and resistance training mimetic (PF-879) on metabolic and performance outcomes in...

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Autori principali: Bernardo, Barbara L., Wachtmann, Timothy S., Cosgrove, Patricia G., Kuhn, Max, Opsahl, Alan C., Judkins, Kyle M., Freeman, Thomas B., Hadcock, John R., LeBrasseur, Nathan K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892469/
https://ncbi.nlm.nih.gov/pubmed/20593012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011307
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