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One-hit wonders of genomic instability

Recent data show that cells from many cancers exhibit massive chromosome instability. The traditional view is that the gradual accumulation of mutations in genes involved in transcriptional regulation and cell cycle controls results in tumor development. This, however, does not exclude the possibili...

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Detalhes bibliográficos
Autor principal: Strunnikov, Alexander V
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892438/
https://ncbi.nlm.nih.gov/pubmed/20482869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-5-15
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