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One-hit wonders of genomic instability

Recent data show that cells from many cancers exhibit massive chromosome instability. The traditional view is that the gradual accumulation of mutations in genes involved in transcriptional regulation and cell cycle controls results in tumor development. This, however, does not exclude the possibili...

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Détails bibliographiques
Auteur principal: Strunnikov, Alexander V
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892438/
https://ncbi.nlm.nih.gov/pubmed/20482869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-5-15
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