Involvement of oxidatively damaged DNA and repair in cancer development and aging

DNA damage and DNA repair may mediate several cellular processes, like replication and transcription, mutagenesis and apoptosis and thus may be important factors in the development and pathology of an organism, including cancer. DNA is constantly damaged by reactive oxygen species (ROS) and reactive...

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Bibliographic Details
Main Authors: Tudek, Barbara, Winczura, Alicja, Janik, Justyna, Siomek, Agnieszka, Foksinski, Marek, Oliński, Ryszard
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2010
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892402/
https://ncbi.nlm.nih.gov/pubmed/20589166
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