Evaluation of an Aerosolized Selective COX-2 Inhibitor as a Potentiator of Doxorubicin in a Non-Small-Cell Lung Cancer Cell Line

PURPOSE: To evaluate the in vitro effects of an aerosolized cyclooxygenase-2 (COX-2) inhibitor, nimesulide, on the cytotoxicity and apoptotic response of doxorubicin against the human lung adenocarcinoma cell line A549. METHODS: Nimesulide was formulated into a metered dose inhaler (MDI) formulation...

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Autores principales: Haynes, Alfred, Shaik, Madhu Sudhan, Chatterjee, Abhijit, Singh, M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2003
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892336/
https://ncbi.nlm.nih.gov/pubmed/14567645
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