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Antitumor Activity of a Novel Antisense Oligonucleotide Against Akt1

The AKT pathway is an important therapeutic target for cancer drug discovery as it functions as a main point for transducing extracellular and intracellular oncogenic signals. Moreover, alternations of the AKT pathway have been found in a wide range of cancers. In the present study, we found that an...

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Hlavní autoři: Yoon, Heejeong, Kim, Deog Joong, Ahn, Eun Hyun, Gellert, Ginelle C., Shay, Jerry W., Ahn, Chang-Ho, Lee, Young Bok
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892285/
https://ncbi.nlm.nih.gov/pubmed/19693774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22311
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