Th17 Cytokines Stimulate CCL20 Expression in Keratinocytes In Vitro and In Vivo: Implications for Psoriasis Pathogenesis

T helper (Th) 17 cells have recently been implicated in psoriasis pathogenesis, but mechanisms of how these cells traffic into inflamed skin are unknown. By immunostaining for interleukin (IL)-17A and IL-22, we show numerous cells present in psoriasis lesions that produce these cytokines. We next fo...

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Bibliografiske detaljer
Main Authors: Harper, Erin G., Guo, Changsheng, Rizzo, Heather, Lillis, Joseph V., Kurtz, Stephen E., Skorcheva, Iliyana, Purdy, David, Fitch, Erin, Iordanov, Mihail, Blauvelt, Andrew
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892172/
https://ncbi.nlm.nih.gov/pubmed/19295614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2009.65
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